Heparin

موضوع: Heparin الجمعة يونيو 01, 2012 5:09 am

Heparin
Is
an anti-coagulant, a component of the blood core, but there is a
concentration not sufficient to prevent blood clotting, and generates
the heparin from the liver cells it is a concentration high in the liver
and is also present in lung cells have been separated and isolated in
salt crystallized from the extract of the liver, lung and is
distinguished from other
being that does not interfere with any test of the test chemical
analysis, heparin is a Mecotiin many sulfuric acid Muccoitin
Polysulphouric - Acid, one of the polysaccharides can be obtained
commercially at the present time of the sodium salts Sodium Heparin or
potassium salt Potassium Heparin or lithium salt Lithium Heparin
Works
as an antidote to heparin thrombin where Antithrombin prevents the
transfer or convert prothrombin to thrombin Thrombin Prothrombin, and so
prevents the formation of fibrin to fibrinogen Fibrin Fibrinogen
clotting and the process in two stages as follows:

Prothrombin    Thrombplastic Activity Factor             ► Thrombin

Fibrinogen    Thrombin             ► Fibrin (blood colt)

And it needs a catalyst to heparin Cofactor to do his job.

Addition
of heparin by 20% and units per ml of blood, and since it does not
dissolve in the case therefore of solution is often used and dried, Alr
walls of the tube to be in direct contact with blood, its effects are
the best we can, and still high prices, its effects are temporary
obstacles to its use in the laboratory when
compared. other anticoagulants, heparin sodium and contains at least
110 units / mg and is usually used concentration of about 0.2 mg / ml of
blood.